For many years, the standard methods used to treat cancer are chemotherapy, radiotherapy or surgery. These treatments use drugs designed to aggressively kill cancer cells that divide rapidly and are effective, but still kill many of an individual's healthy cells and cause serious side effects. It has only been in the last few decades that the emergence of a new approach to cancer therapy has attracted attention. Researchers have focused on the idea of ​​cancer immunotherapy. The first immunotherapy maneuver was performed in 1860. A man named William Cooley decided to inject bacteria into tumors. He noticed that the bacteria provoked an immune response in the patients and this caused the tumor to regress. This was the first example that demonstrated that we could use patients' immune responses to fight a tumor. Scientists have struggled and attempted to create effective cancer treatments based on Cooley's observations. To understand how immunotherapy works, it is helpful to know how the immune system works to fight cancer. Cancer cells have substances on their surface called tumor antigens that raise an alarm in the immune system indicating the presence of cancer. Antigen-presenting cells (APCs) roam the body seeking out and ingesting tumor antigens. APCs then activate B cells and T cells. B cells differentiate into plasma cells and secrete antibodies that bind to tumor cells and mark them for elimination (a humoral immune response). When T cells are activated, they proliferate and expand, seeking out and destroying cells carrying tumor-specific antigens (a cellular immune response). Sometimes the immune response does not destroy all tumor cells and this... middle of paper... could be another area of ​​research that could enhance anti-tumor activity. By creating better antibodies, such as rituximab and others, we are able to better target the tumor cell. There are many targets on our body's immune cells and being able to specifically target them and boost the immune system to function better than it already can prove beneficial and harnessing this power can lead to a dramatic impact on the pathway. we cure cancer. Maintaining and preserving the quality of life of patients and seeking a permanent cure is what scientists are looking for. Improving the effectiveness of these immunotherapy treatments can lead to significant advances, including long-term remission and the ability to treat patients with difficult-to-treat cancers. I look forward and look forward to seeing the advances that will be made in this field or research in the near future.