The large intestine surrounding the small intestine is made up of the cecum; appendix; ascending, transverse, descending and sigmoid colon; rectum; and anal canal1. The large intestine differs anatomically from the small intestine by the presence of four 1:1 features. Omental appendages: accumulations of fat covered by peritoneum similar to the omentum2. Teniae coli: Thickened bands of smooth muscle that begin at the base of the appendix as a single band and then separate into three bands to run the length of the remainder of the large intestine to the rectosigmoid junction where they again become a united longitudinal layer band around the rectum3. Haustra: sacculation/sacs within the semilunar folds4. The internal diameter/caliber is greatest in the large intestine Cecum and appendix The cecum; approximately 7.5 cm long and wide, it is a blind intestinal pouch and constitutes the first part of the large intestine1. It is inferior to the ileocecal junction and is located in the inguinal region/right iliac fossa1. It is an intraperitoneal structure however it does not have a mesentery1. It is held in place in the right iliac fossa by one or more cecal folds of the peritoneum1. The relationships of the cecum1: o Continuous with the ascending colon at the level of the opening of the ilium on the medial side o In contact with the anterior abdominal wall o The appendix is ​​attached to the posteromedial wall o Superiorly to the inguinal ligament; within 2.5cm; and rests posteriorly on the right iliac fossa. The vermiform appendix, meaning worm, is on average a narrow, blind-ended tube 6-10 cm long that arises on the posteromedial aspect of the cecum inferior to the ileocecal junction1. It is suspended from the terminal ileum via a short triangle... in the center of the paper... along the left colic artery1. It then moves on to the inferior mesenteric lymph nodes1. Lymph from the left colic flexure may drain into the superior mesenteric lymph nodes or the inferior mesenteric lymph nodes.1. The innervation distal to the left colic flexure has a sympathetic innervation from the lumbar part of the sympathetic trunk via the lumbar/abdominopelvic splanchnic nerves, the superior lumbar/abdominopelvic splanchnic nerves. mesenteric plexus and the periarterial plexuses that follow the inferior mesenteric artery and its branches1. Parasympathetic nerve supplies form the pelvic splanchnic nerves via the inferior hypogastric plexus and nerves1. Works Cited1. Moore KL, Dalley AF, Agur AMR. Clinically oriented anatomy. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2010, p.246-253; 411-414.2. Netter, F.H. Atlas of human anatomy. 5th ed. Philadelphia: Saunders Elsevier; 2009. Plate 373.