IntroductionBiPAP is a form of non-invasive mechanical ventilation used on patients with acute respiratory failure. Many of these patients undergo non-invasive ventilation due to COPD exacerbations of an infectious nature, with congestive heart failure and ventilation parameters based on clinical assessment and changes in arterial blood gases. Two different studies were conducted on COPD patients, using a BiPAP machine to improve flare-ups and their activities of daily living. There are many positive outcomes for using these non-invasive ventilators, however, if used incorrectly, negative outcomes or no changes are always possible. be ventilated and move trapped carbon dioxide out of the lungs. When there is too much carbon dioxide in the blood, the gas moves across the blood-brain barrier and causes acidosis within the body because not enough carbon dioxide is being expelled through ventilation. The BiPAP machine allows positive pressure to enter the lungs, expand to the alveoli, and create movement of air and blood. Two different machines were used as part of the study; a regular BiPAP ventilator and bi-level positive airway pressure – spontaneous/timed with assured medium volume pressure support, or AVAPS. The latter machine uses a setting for a set tidal volume and adjusts based on inspiratory pressure. A total of 22 patients were admitted for the study, with 11 simply for the BiPAP side and the other half for the BiPAP using AVAPS. Each patient had to fall within a selected APACHE II score range within 4, ag...... half of the document ......deemed necessary to improve the life of the person and those around them. Works Cited Claudett Killen, HB , Claudett Monica, B., Wong MCS, Martinez AN, Espinoza RS, Montalvo M., Rodriguez AE, Diaz GG, Andrade MG (2013). Noninvasive mechanical ventilation with assured medium volume pressure support (AVAPS) in patients with chronic obstructive pulmonary disease and hypercapnic encephalopathy. BMC Pulmonary Medicine, 1.12pm. Retrieved from http://www.biomedcentral.com/1471-2466/13/12. Sclauser Pessoa, I. B., Costa, D., Velloso, M., Mancuzo, E., Reis, M. S., & Parreira, V. F. (2012). Effects of noninvasive ventilation on patients with dynamic hyperinflation of COPD during activities of daily living with the upper extremities. Brazilian Journal of Physical Therapy, 16(1), 61-67. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22441230.